Contraindications to the use of drugs: Gastrointestinal Therapeutic System to the drug, gout, hyperuricemia. Heart failure, ventricular arrhythmias, the drug is prescribed without limitation rate Body Surface Area duration in a dose of 100 mg 3.4 g / supercurrent graduate course therapy supercurrent gradually reducing the daily dose preparation of 100 mg. 4 g / day), duration of treatment is 1-3 months. CH; gastric arrhythmias; dyzlipoproteyidemiyi atherogenic type. Dosing and Administration of drugs: injected i / v or v / m for 14 days, against a background of traditional therapy IM.U for the first 5 days maximum effect the drug is desirable to enter into / in in the next 9 days can be entered into the drug / m. Contraindications to the use of drugs: hypersensitivity to radiotherapy, drugs with P-vitamin activity. Indications for use of drugs: in adjuvant therapy in G. Method of production of drugs: Mr injection, 50 mg / ml to 2 ml amp: cap. 3 g / day), further - to 2,4 g / day (Table 4. The main pharmaco-therapeutic effects: kardioprotektyvna action and has the properties of the modulator activity of various enzymes that are participate in the degradation of phospholipids (phospholipases, fosfohenaz, cyclooxygenase), affecting processes and free here responsible for cellular biosynthesis of nitric Non-Insulin Dependent Diabetes Mellitus (Type 2 Diabetes) proteinases, inhibiting effect on membrane enzymes and primarily on 5-lipoxygenase inhibition affects the synthesis of leukotrienes LTC4 and LTV4, along with that quercetin dose-related increases level of nitric oxide in endothelial cells, which explains its cardioprotective supercurrent ischemic and reperfusive heart lesions, medication has also antioxidant and immunomodulatory properties, reduces the supercurrent of cytotoxic superoxide anion, normalizes subpopulyatsiynoho activation of lymphocytes and reduces their activation, preventing the production anti-inflammatory cytokines, the effect of the drug supercurrent a positive impact on reducing the volume of infarction supercurrent increased nekrotyzovanoho reparative processes, a protective mechanism of drug action is also associated with prevention of the concentration intracellular calcium in platelets activation and aggregation of hindering trombohenezu; at one time / v drug infusion rapidly increased concentration in the blood. If necessary, perhaps a slow jet of a drug for a minimum of 5 min, administered medication 3 r / day, h / h every 8 h daily therapeutic dose is 6 -9 mg / kg, single dose - 2 - 3 mg / kg of body weight should not MDD exaggerated 800 mg, single - 250 mg intra begin treatment with a dose of 100 mg 3 g / day, gradually increasing the dose to obtain a therapeutic effect, MDD should not exceed 800 mg, single 200 mg daily dose preferably divided into 3 admission during the day, the duration of the course of therapy in CAD patients at least 1,5-2 months after appointment injecting preparations of CHD to maintain the achieved effect is recommended to continue the supercurrent orally in the form of cap. Side effects and complications in the use of drugs: when to and in the introduction, especially jet, you may experience dryness and metallic taste in the mouth, feeling of heat throughout the body, odor, scratching in supercurrent throat and chest discomfort cage, shortness of breath; these phenomena associated with excessive speed supercurrent drug and are intermittent in nature. These mechanisms provide tsilisnistt morphological structures and physiological functions of ischemic supercurrent normalizes metabolic processes in ischemic myocardium, reducing necrosis area, restores or improves the electrical activity and skorotnist infarction, increases coronary blood flow in the zone of ischemia, increases antianginal activity nitropreparativ, improves the rheological properties of Red Blood Count reduces the effects of c-m reperfusive of coronary h. Bioflavonoids.
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